A Normal C Reactive Protein and Significant Bacterial Infection in Literature review

A Normal C Reactive Protein and Significant bacterial Infection in Children with Fever - Literature review ExampleOne of the most common reasons for essential Department (ED) visit is the fever. Fever accounts to approximately 10 35% of admissions in children younger than three historic period of age (Nuttall, 2003 Andreola et al., 2007 Behjati 2008 Liu et al, 2008). In this age group, severe bacterial infections or SBI represents to about 10 25% however, Andreola et al (2007) noted that this diagnosis is frequently confusing particularly with the absence of localising findings. Hence, a need for specific and irritable laboratory markers for infection is required because of the presence of clinical findings such as body temperature. More than a decade ago, an algorithm which incorporates with laboratory findings, such as white blood cell count and implicit neutrophil count was published and was proven to be useful in the medical practice especially in the identification child ren who are at higher risk of severe bacterial illness. Additional markers such as C activated protein (CRP) and procalcitonin (PCT) are maybe useful (Nuttall, 2003 Andreola et al, 2007). In 1930, CRP is discovered by Tillett and Francis as C Polysaccharide calculate called as fraction C from the sera of an acutely ill patient. In 1941, fraction C was found to be a peptide instead of a polysaccharide, thus renamed as C reactive peptide. In 1950, it was reported that CRP can be detected in more than 70 types of disorders. Carlan added that CRP can be normal in invasive bacterial disease, and produces the largest, the most rapid, and most quantifiable acute response to touchwood and infection.